Special Issue "Targeting the Ubiquitin Pathway in Cancer"
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 June 2020).
Interests: Head and neck cancer; cell cycle; ubiquitin-proteasome pathway; invasion; metastasis; oral pathology
The ubiquitin–proteasome system (UPS) is a common mechanism by which cells renew their intracellular proteins and maintain protein homeostasis. Recently, abnormal regulation of UPS has been found to be involved in various diseases, including cancer. A series of enzymes known as E1s (ubiquitin-activating enzymes), E2s (ubiquitin-conjugating enzymes), various E3s (ubiquitin ligases), and deubiquitinating (DUB) enzymes in the UPS could serve as potential drug targets in cancers. In addition, chimeric small molecules which are designed to induce degradation of their target proteins via the UPS can be used for cancer therapy. In this Special Issue, we focus on abnormalities of the ubiquitin–proteasome system and their potential of therapeutic target in cancer.
Dr. Yasusei Kudo
Manuscript Submission Information
Manuscripts should be submitted online at www.ynsqex.icu by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Ubiquitin-proteasome pathway
- Anti-cancer drug